A Pilot, First-in-Human, Pharmacokinetic Study of 9cUAB30 in Healthy Volunteers
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چکیده
منابع مشابه
A pilot, first-in-human, pharmacokinetic study of 9cUAB30 in healthy volunteers.
9cUAB30 is a synthetic analog of 9-cis-retinoic acid with chemopreventive activity in cell lines and in animal models. The purpose of this first-in-human evaluation of 9cUAB30 was to evaluate the single-dose pharmacokinetic profile and toxicity of the compound in healthy volunteers at 3 dose levels. This study enrolled 14 patients to receive a single dose of 5, 10, or 20 mg of 9cUAB30. Plasma a...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2010
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-10-0149